FSL0370
- Structure
- InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
- InChIKey=BSYNRYMUTXBXSQ-UHFFFAOYSA-N
- Synonyms
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- Origin
- Chemically synthesized
- Biological activities
- Inhibition of the production of prostaglandins and thromboxanes
- Therapeutic
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Analgesic and antipyretic
Antiinflammatory
Antiplatelet
- Target
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Cyclooxygenase
- Assay information
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Inhibition of the production of prostagrandins and thromboxanes (1, 2) by irreversible inhibition of COX (IC50: 5 μg/ml for COX-1, 210 μg/ml for COX-2)
Growth inhibition against various cancer cell linces at sub-mM range