2016 Presentation
1st UGAS, Iwate University International Symposium 2016
Dec. 17th - 18th, 2016, Morioka, Iwate-ken, Japan
- Shota Uesugi, Makoto Muroi, Yasumitsu Kondoh, Tetsuro Yamashita, Yoshihito Shiono, Masaru Hashimoto, Hiroyuki Osada, Ken-ichi Kimura
Identification of the molecular targets and electrophilic properties of covalent-binding anti-cancer compounds.
Dec. 14th - 15th, 2016, Tokyo, Japan
- Muroi M, Kawatani M, Kawamura T, Futamura Y, Osada H
Analysis of MTH1 inhibitors by ChemProteoBase, the drug-target analysis system based on proteomic profiling.
Nov. 30th - Dec. 2nd, Tokyo, Japan
- Toshiyoshi Yamamoto, Takahiro Kagemoto, Kurin Iimura, Yasumitsu Kondoh, Kaori Honda, Hiroyuki Osada, Shohei Sakudai.
Effect of fluoropyrimidines on aflatoxin production.
Nov. 30th, Munich, Germany
- Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanakaa M, Honda K, Osada H
Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival
Asian 3 round table on nucleic acids and chemical probes research hub
Sep. 22th, 2016, Fukuoka, Japan
- Kawamura T, Kawatani M, Osada H
The role of the MTH1 enzyme in cancer gave rise to controversy
9th Joint Natural Products Conference 2016
Jul. 26th, 2016, Copenhagen, Denmark
- Motoyama T, Tanaka Y, Osada H
Activation of fungal secondary metabolism by disturbance of the two-component signal transduction system and identification of the nectriapyrone biosynthetic gene cluster
17th Tetrahedron Symposium
Jun. 29th, 2016, Sitges, Spain
- Osada H
Stereospecific ring formation in biosynthesis of specialized microbial metabolites
- Kondoh Y, Honda K, Hiranuma S, Shimizu T, Osada H
Comparative chemical array screening of p38γ/δ MAPK inhibitors by focusing on a single gatekeeper residue difference between p38α/β and p38γ/δ.
May 11th, 12th, 2016, Berlin, Germany
- Jonas Aretz
Upendra Rao Anumala, Paul Robin Wratil, Hannes Baukmann, Eike-Christian Wamhoff, Jonas Hanske, Hoang Giang Nguyen, Yasumitsu Kondoh, Kaori Honda, Nobumoto Watanabe, Hiroyuki Osada, Werner Reutter, Marc Nazaré, Christoph Rademacher.
The Unusual Suspects: Fragment Screening of Carbohydrate-binding Proteins.
RIKEN-Max Planck Joint Research Center for Systems Chemical Biology The 5th Symposium
Apr. 17th - 20th, 2016, Berlin, Germany
- Kawamura T, Kawatani M, Kondoh Y, Muroi M, Futamura Y, Aono H, Tanaka M, Honda K, Osada H.
Identification of MTH1inhibitors by chemical arrays
- Muroi M, Tanaka M, Osada H.
Expansion of ChemProteoBase for the analysis of compounds affecting cancer metabolism
- Watanabe N, Osada H
14-3-3 protein-porotein interaction inhibitors identified by high throughput screening
- Kondoh Y, Honda K, Hiranuma S, Shimizu T, Osada H
Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.
- Jonas Aretz, Yasumitsu Kondoh, Kaori Honda, Upendra Rao Anumala, Marc Nazaré, Nobumoto Watanabe, Hiroyuki Osada, Christoph Rademacher
Fragment arrays for early druggability assessments.
Feb. 16th - 20th, 2016, Maui, Hawaii, USA
- Hiroyuki Osada
Screening of small molecule compounds with activity to selectively inhibit the cancer stem cell properties.
- Nobumoto Watanabe, Hiroyuki Osada
Discovery and analyses of 14-3-3 protein-protein interaction inhibitors identified by high throughput screening
- Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
Novel screening approach for drug discovery from virtual mirror-image library of natural products
The 8th Korea-Japan Chemical Biology symposium
Jan. 19th, 2016, Naha, Okinawa, Japan
- Yun CS, Motoyama T, Osada H.
Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme
- Miyazawa H, Takahashi S, Shimizu T, Nogawa T, Osada H
Characterization of middle chain fatty acyl-CoA ligase responsible for the biosynthesis of 2-alkylmalonyl-CoAs for polyketide extender unit
- Kato N, Nogawa T, Hirota H, Takahashi S, Jang JH, Ahn JS, Osada H
Discovery of a new enzyme involved in the stereoselective decalin formation during equisetin biosynthesis
- Otaka J, Futamura Y, Osada H.
Bioactive compounds from Plant Roots
- Futamura Y, Kawatani M, Aono H, Muroi M, Tanaka M, Osada H.
Phenotypic screening of small molecules targeting cancer metabolism
- Katsuyama S, Sugino K, Sasazawa Y, Nakano Y, Aono H, Kawatani M, Osada H, Simizu S.
A novel osteoclastogenesis inhibitor targeting nucleoside transporters